From Manual Cell Counting to Smart Cell Culture Monitoring
Discover how the health status of your suspension cell culture is tracked by an automated, sample and label-free 3D holographic microscope that records 59 parameters at a single-cell level.
How Automation Has Changed the Way we Count Cells
- Learn how the evolution of cell counting technologies has improved measurement assays
- Discover an in-depth comparative study: off-line versus in-line cell monitoring methods
- Find out how automated systems enable fast and accurate cell counting
Prof. Dr. Frank Gudermann, Erik Kakes, Philip Mathuis
- Viable Cell Density Comparison
- Automated Cell Viability Monitoring
- Cell Browser: a Cell by Cell Review of the Culture
*Click on the case of interest to access the complete version
On-line Quantitative Cell Analyser
All you need to know about the iLine F technology features and how it works in one single document.
Automated Suspension Cell Culture Monitoring In Stirred Tank.
Case study comparing the iLIne F microscope with classical light microscopy for the monitoring of CHO cells. Results demonstrated the good correlation of cell density and the cell viability and showed how the label-free approach provides full data per cell. Not only for the whole experiment but also for validation, QC, audit, etc.
Advanced Analysis & Machine Learning Software
- Real-time measurement of live and dead cell
- Single cell analysis based on 59 parameters
- Cell culture parameters, cell viability, viable cell density, aggregate rate
Continuous Cell Culture Monitoring
Identified needs in Biopharma and innovative solutions for cell culture monitoring were presented by Ovizio at Flanders Bio Knowledge for growth on May 21st.
ESACT Meeting Poster
Continuous Suspension Cell Culture Monitoring in Bioreactors
In this study, we compared the results generated by the iLine-F with 2 reference methods applying Trypan-Blue staining: a) manual counting and b) the off-line counter Vi-Cell XR (Beckman Coulter). The iLine-F was set to generate 2 cell count cycles per hour and the culture was left to grow in batch mode for a total of 13 days.